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This started as an effort to figure out which paragon and epic tier monsters had attacks potentially subject to mettle and evasion and then use that information to judge their value as feats.

I found only 22 paragon monsters and 12 epic monsters in the MM.
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Aside from dracoliches and Storm Giants or Titans, the miss effect for all the relevant powers is only half damage. Each of the monsters has, and may be expected to use, other attacks as alternatives, using these powers no more than once every 2-3 rounds.

My conclusion is that the feats come into play too rarely against monsters, and have too little impact when they do, to be worthwhile at present.

The traditional use for these feats of "fireballing the rogue" is also unlikely to be of value. In epic, spell accuracy solves the problem for the wizard; the 4e cleric has never had it. Even in Paragon, it is unlikely for the character with evasion to possess a defense sufficiently ahead of the wizard to make this advisable, and the present list of powers doesn't present a blast or area attack devastating enough to make it worthwhile to build a character around.
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The other traditional use (dodging a trap) has also become less of a priority. As the effects of a failed disable attempt for DMG traps have no miss effects, there is no particular advantage to having the party's thievery skill character also have evasion or mettle.

Mettle is a solution in search of a problem, and presently not worth taking without unusual and campaign-specific reasons.

That said, evasion may not be a bad spare feat to take, particularly if you expect a lot of dragons in your campaign. An anti-dragonbreath feat is a bit specialized, but not necessarily suboptimal.

Excellent post. I haven't had a chance to go through the MM in any detail yet. My defensive fighter build currently has both evasion and mettle in it because I figured, "I'm a defender with pretty high saves, I clearly need this." Given your post, I may have to rethink that.