I thought some people here might be interested in this. Metamorphosis Alpha was the precursor to GW, published in 1976. The general premise of the game was that Earth had sent a gigantic colony spaceship to a nearby star. Along the way, the ship passed through a radiation cloud, causing the central computer to malfunction and producing mutations in the people, flora and fauna aboard. The players were humans and/or mutants living on the ship several generations after the breakdown of civilization exploring their 'world.'
Saw this announcement today:
Signal Fire Studios LLC is proud to announce that 2010 will see the publication of the newest incarnation of the very first science fiction role playing game, Metamorphosis Alpha
! Using the Dungeons & Dragons 4th Edition game rules, players take on the role of mutated humans, plants, and animals and experience sci-fi action-adventure.
You can read more about it here: Signal Fire Studios
I think the release date for it may have been moved back to Q1 2011.