Combining two campaigns?

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I'm considering combining the Freeport Series and Pushing it into The Crimson Throne series. The idea is Drac casts his madness spell, and the heroes kill him, then this is where Crimson Throne picks up as Madness over takes the city into riots. Will this work? Can this work? Not too sure of the ramifications. Any help/suggestions would be helpful. Thanks in advance!

JK Wolf