Using the cleric daily power of 25lvl Seal of Binding is sure wint when you strike a solo monster with it and you have Divine Regeneration from Epic Destiny - Demigod. This is so broken. Target is stunned. You don't take any damage couse you gain regeneration 24-28 or so (damage dealt to you and target is 2k10 + about 14) and the target is slowly killed. You can sustain for 50 rounds. LOL.